Thy-1+ and Thy-1- natural killer cells. Only Thy-1- natural killer cells suppress dendritic cells.

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Thy-1+ and Thy-1- natural killer cells. Only Thy-1- natural killer cells suppress dendritic cells

Cells enriched for NK activity (poly I:C induced, x-ray resistant, and nonadherent), include two phenotypically and functionally different populations. Both populations of NK cells are AGM1+, Ly-1.1-, Ly-2.1-, Ia-, and have the morphology of large granular lymphocytes. One population, however, is Thy-1+ while the second population is Thy-1-. Thy-1+ NK cells lyse YAC-1 and P815 target cells; Thy...

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THY 1 ( Thy - 1 cell surface antigen )

Transcription of THY1 is initiated at multiple sites producing an approximately 5591 bp transcript. After splicing, the transcript is reduced to 2143 bp. Transcriptional regulation for tissue-specific expression of Thy-1, as well as for controlling expression in cell sub-populations, and in some cancers, is governed by a number of mechanisms. For tissue-specific transcriptional regulation, the ...

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Generation of natural killer cells from Thy 1.1+ bone marrow precursor cells in the rat.

We have recently described a long-term bone marrow culture (LTBMC) system in the rat for the generation of natural killer (NK) cells from bone marrow (BM) precursors in the presence of interleukin-2 (IL-2). We found that the LTBMC-conditioned medium was essential to render the NK precursor cells responsive to IL-2. In this report, we isolated by flow cytometric cell sorting Thy 1.1+ BM cells, w...

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"Anomalous" Thy-1+ killer cells in allogeneic and F1-anti-parental mixed leukocyte culture. Relation to natural killer cells and allospecific cytotoxic T lymphocytes

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The Thy-1-bearing cell of murine epidermis. A distinctive leukocyte perhaps related to natural killer cells

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ژورنال

عنوان ژورنال: Journal of Experimental Medicine

سال: 1986

ISSN: 0022-1007,1540-9538

DOI: 10.1084/jem.163.4.1012